Hierarchical control over effortful behavior by rodent medial frontal cortex : a computational model

The anterior cingulate cortex (ACC) has been the focus of intense research interest in recent years. Although separate theories relate ACC function variously to conflict monitoring, reward processing, action selection, decision making, and more, damage to the ACC mostly spares performance on tasks that exercise these functions, indicating that they are not in fact unique to the ACC. Further, most theories do not address the most salient consequence of ACC damage: impoverished action generation in the presence of normal motor ability. In this study we develop a computational model of the rodent medial prefrontal cortex that accounts for the behavioral sequelae of ACC damage, unifies many of the cognitive functions attributed to it, and provides a solution to an outstanding question in cognitive control research-how the control system determines and motivates what tasks to perform. The theory derives from recent developments in the formal study of hierarchical control and learning that highlight computational efficiencies afforded when collections of actions are represented based on their conjoint goals. According to this position, the ACC utilizes reward information to select tasks that are then accomplished through top-down control over action selection by the striatum. Computational simulations capture animal lesion data that implicate the medial prefrontal cortex in regulating physical and cognitive effort. Overall, this theory provides a unifying theoretical framework for understanding the ACC in terms of the pivotal role it plays in the hierarchical organization of effortful behavior

Initial Conditions, Institutional Dynamics and Economic Performance: Evidence from the American States

Using state-level data from the United States, we find that differences in colonial legal institutions affect the current quality of state legal institutions. These differences in colonial legal institutions arose because some states were settled by Great Britain, a common law country, and other states were settled by France, Spain, and Mexico, all civil law countries. To explain these findings, we develop a transplant-civil law hypothesis that highlights the disruption associated with large-scale legal transplantation and the possible relative inefficiencies of colonial civil law. We find strong support for the transplant-civil law hypothesis. Our results are robust to inclusion of additional variables capturing climate, geography, initial population and resource endowments. Given the 150-200 year gap between the initial conditions and the measures of the current quality of legal institutions, we provide indirect evidence on the persistence of legal institutions. We then use initial legal systems and climate to quantify the substantial impact of current institutions on current economic performance.http://deepblue.lib.umich.edu/bitstream/2027.42/40001/3/wp615.pd

Forms of early walking

Children in the first weeks of independent locomotion display a wide variety of walking forms. The walking forms differ in mechanical strategy and concern with balance. Three extreme walking forms are presented: the Twister, who uses trunk twist, the Faller, who uses gravity, and the Stepper, who remains balanced as much as possible. Each walking form is presented as a ''d-space'', a mathematical format combining continuous and discrete aspects, developed to express the sequence and pattern of a movement without the inappropriate precision of a physical trajectory. The three d-spaces represent analyses of three extreme modes of early walking. They are used to generate the variety of early walking forms and to predict mixtures of mechanical strategies as children mature and converge to more similar walking forms over the first few months of independent locomotion. (C) 1995 Academic Press Limite

Absence of long-range superconducting correlations in the frustrated 1/2-filled band Hubbard model

We present many-body calculations of superconducting pair-pair correlations in the ground state of the half-filled band Hubbard model on large anisotropic triangular lattices. Our calculations cover nearly the complete range of anisotropies between the square and isotropic triangular lattice limits. We find that the superconducting pair-pair correlations decrease monotonically with increasing onsite Hubbard interaction U for inter-pair distances greater than nearest neighbor. For the large lattices of interest here the distance dependence of the correlations approaches that for noninteracting electrons. Both these results are consistent with the absence of superconductivity in this model in the thermodynamic limit. We conclude that the effective 1/2-filled band Hubbard model, suggested by many authors to be appropriate for the kappa-(BEDT-TTF)-based organic charge-transfer solids, does not explain the superconducting transition in these materials.Comment: 9 pages, 7 figures. Revised version to appear in Phys. Rev.

Fatty acid bioaccessibility and structural breakdown from in vitro digestion of almond particles.

Previous studies have shown that the size of almond particles influences lipid bioaccessibility during digestion. However, the extent of structural breakdown of almond particles during gastric digestion and its impact on lipid bioaccessibility is unclear. In this study, in vitro digestion of almond particles was conducted using a dynamic model (Human Gastric Simulator) and a static model (shaking water bath). Structural breakdown of particles during the gastric phase occurred only in the Human Gastric Simulator, as evidenced by a reduction in particle size (15.89 ± 0.68 mm2 to 12.19 ± 1.29 mm2, p < 0.05). Fatty acid bioaccessibility at the end of the gastric phase was greater in the Human Gastric Simulator than in the shaking water bath (6.55 ± 0.85% vs. 4.54 ± 0.36%, p < 0.01). Results showed that the in vitro model of digestion which included peristaltic contractions (Human Gastric Simulator) led to breakdown of almond particles during gastric digestion which increased fatty acid bioaccessibility

Rapid characterization of the ultraviolet induced fiber Bragg grating complex coupling coefficient as a function of irradiance and exposure time

We report the application of optical frequency domain reflectometry and a discrete-layer-peeling inverse scattering algorithm to the spatial characterization of the UV induced complex coupling coefficient during fiber Bragg grating growth. The fiber grating is rapidly characterized using this technique to give irradiance dependent growth as a function of exposure time, thereby providing the complete characterization of the coupling coefficient in the form of a "growth surface," which is related to the fiber's photosensitivity. We compare measurements of fiber Bragg grating growth in SMF-28 when exposed to continuous wave 244 nm irradiation from 0 to 90 W cm(-2) for exposure times up to 3230 s with a selection of other fibers including high germanium concentration fiber and erbium doped fiber. (c) 2007 Optical Society of America

Ion mass spectrometer

An ion mass spectrometer is described which detects and indicates the characteristics of ions received over a wide angle, and which indicates the mass to charge ratio, the energy, and the direction of each detected ion. The spectrometer includes a magnetic analyzer having a sector magnet that passes ions received over a wide angle, and an electrostatic analyzer positioned to receive ions passing through the magnetic analyzer. The electrostatic analyzer includes a two dimensional ion sensor at one wall of the analyzer chamber, that senses not only the lengthwise position of the detected ion to indicate its mass to charge ratio, but also detects the ion position along the width of the chamber to indicate the direction in which the ion was traveling